Reverse Cholesterol Transport (RCTr) is the mechanism by which excess cholesterol from peripheral tissues is transported to the liver for hepatobiliary excretion, thereby inhibiting foam cell formation and the development of atherosclerosis. Exercise affects RCTr, by influencing high-density lipoprotein cholesterol (HDL) through remodeling and by promoting hepatobiliary sterol excretion. Moderate intensity and longer-term training has a greater effect on RCTr elements than low intensity training. There a few studies examining high intensity training which warrants further investigation.
Saleh Rahmati-Ahmadabad, David Robert Broom, Abbass Ghanbari-Niaki, Hossein Shirvani, Effects of exercise on reverse cholesterol transport: A systemized narrative review of animal studies, Life Sciences, Volume 224, 2019, Pages 139-148, ISSN 0024-3205, https://doi.org/10.1016/j.lfs.2019.03.058. https://www.sciencedirect.com/science/article/pii/S0024320519302218.
